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Extruders
| How Extrusion Conditions Influence the Properties of Starch Compounds This webinar examines the influence that twin-screw extrusion has on production of a potato starch compound. It explains how users can more adeptly design a starch matrix to meet required product properties. The Thermo Scientific™ Process 11 Hygienic twin-screw extruder allows the user to influence texture, stability and further processability of the final product by controlling different process parameters such as: screw configuration screw speed feeding rate temperature Behavior of the resulting starch matrix is further investigated via rheology for a precise analysis of the final product. Target audience: Scientists and Engineers involved in food processing of products based on starch compounds. | Watch webinar now |
| Twin Screw Compounding–Introduction and Scale-Up New functional polymers are continuously taking over new applications in all areas. The compounding process is a decisive factor in development to ensure that the properties of the active ingredients meet the requirements. This seminar is concerned with the principles of compounding based on selected examples from the industry. A further focal point is the scale transfer from research and development to the production process (scale-up). Target audience: Scientists, engineers, and experienced staff members from the polymer industry who are involved in the development and testing of new types of polymer compounds as well as their processing. | Watch webinar now |
| Extrusion Rheology–Use of the Torque Rheometer This webinar is intended for all newcomers and users who work with torque rheometers and laboratory extruders and use them for rheological measurements. Here extruder rheology is illustrated using a series of practical examples and linked with actual processes. Torque rheometers–design and applications Comparison between extruder rheology and high pressure capillary rheology Principles of extruder rheology Applications for round and slotted capillary nozzles Description of measuring procedure, interpretation of flow and viscosity curves in terms of process characteristics and processability, as well as influence of processing aids, color pigments, fillers, lubricants, and additives Target audience: This webinar is intended for all newcomers and users who work with torque rheometers and laboratory extruders and use them for rheological measurements. | Watch webinar now |
| Mixer Test–A Versatile Tool for Polymer Processing This webinar involves structure and applications for torque rheometers and measuring mixers, including measuring mixers for routine monitoring and production of small sample batches. Interpretation of measuring curves in terms of gelatinization and plastification behavior Vulcanization and curing times Network behavior Thermal stability tests Absorption capacity Processing characteristics Processability Target audience: Employees involved in the quality assurance, development, and testing of polymer compounds and rubber mixtures as well as their processing. | Watch webinar now |
| MIM/PIM Application: Laboratory Mixer, Compounding, Rheology Metallic powder and ceramic powder injection molding (MIM/PIM) is a powder metallurgy shaping process, allowing economical production of small components with a complex shape. Target audience: This webinar is intended for all those interested in learning more about these technologies. | Watch webinar now |
Pharmaceutical extruders
| 3 Part Webinar Series: Streamline Drug Development Part 1: Incorporating twin-screw extruders into a continuous manufacturing process Learn how to overcome drug formulation and manufacturing challenges. In this webinar, we examine how a modular approach to continuous pharmaceutical processes using twin-screw extruders can help shorten the time from drug development to market. Part 2: Producing drug delivery systems from solubility enhancement to implants Hot melt extrusion (HME) is a powerful and versatile tool for modern pharmaceutical formulation development. It can be used for many applications from increasing bioavailability to novel drug delivery methods. Part 3: Raman spectroscopy – a powerful tool in process understanding and formulation development Successful formulation of a drug delivery system requires a comprehensive understanding of polymer and active pharmaceutical ingredient (API) interaction. Simultaneous analysis using rheology and Raman spectroscopy can help you characterize the crystallization behavior of drug delivery systems and help tailor their properties to meet final drug requirements. | Watch the webinar(s) |
| Downstream Options for Melt Extrusion This webinar reviews controlled cooling and shaping of post-extrusion materials. We discuss options for die designs and dosage forms served by hot-melt extrusion (HME). We review the uses and advantages of strand line, chill roll, chather/films, and injection molding downstream handling for creating pellets, micropellets or flakes for milling, controlled cooling to manage morphology, and transdermal applications. Considerations during formulation development for downstream handling, reproducibility, drug release, and storage are also covered. Influence on HME process parameters on the downstream process Strand granulation Chill-rolling Injection molding as possibilities for downstreaming Alternative processes for melt processing Target audience: Scientists, engineers, and staff members from pharmaceutical formulation and process development who want more information on the possibilities of downstreaming in HME. | Watch webinar |
| Advances in Continuous Granulation This webinar is a presentation of a modular approach to continuous granulation. It discusses technological possibilities from mixing to finished product, and comparison of granulation characteristics from classic batch methods using a twin-screw extruder. Target audience: Scientists, engineers, and experienced staff members from pharmaceutical process development involved in the development and production of medications in solid form. | Watch webinar |
| Scale-up of a Hot-melt Extrusion Process–Process Parameters and Their Scalability Hot-melt extrusion (HME) has been advancing for a number of years for formulating active ingredients with low solubility. On the basis of a case study a systematic approach to scale-up using critical process parameters is presented. Target audience: Scientists, engineers, and workers in research, process development, and production, actively using twin-screw extruders in the pharmaceutical industry, who want to be introduced to a systematic approach of process scale-up. | Watch webinar |
| Twin-Screw Processes in Pharma–An Introduction Hot-melt extrusion (HME) has been advancing for a number of years for formulating active ingredients with low solubility. The HME process is presented and discussed in detail using practical examples. The use of the extruder for moisture extrusion and granulation is presented. Target audience: Scientists, engineers, and managers in research, process development, and production, desiring a glimpse into the various areas of application for twin-screw extruders in the pharmaceutical industry. | Watch webinar |