Pharma e-Symposium: Advancements in Drug Development and Formulation

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September 14, 2022
10:00 a.m. – 12:45 p.m. EDT | 15:00 p.m. – 17:45 p.m. BST | 16:00 p.m. – 18:45 p.m. CESTSeptember 15, 2022
10:00 a.m. – 11:45 a.m. EDT | 15:00 p.m. – 16:45 p.m. BST | 16:00 p.m. – 17:45 p.m. CESTAttend this e-symposium to gain insights into the latest research and innovative solutions in drug development and formulation. Learn how you can shorten your time-to-market, reduce development costs, increase yield, and assure quality and pharmacopoeia compliance throughout the drug development process.

You will learn useful strategies regarding oral solid dosage (OSD) formulation, drug delivery systems, and implant development, as well as process R&D and manufacturing. In addition, the series covers several key techniques:

•	Hot-melt extrusion for OSD and implants	•	Twin-screw granulation and continuous manufacturing
•	Utilizing PAT for process monitoring and quality assurance
•	Raman microscopy for diagnosis and final product verification
•	UV-Visible spectroscopy for quality control and adherence to pharmacopoeial standards

Register below by clicking on the link(s) to attend the sessions of interest to you; if registered, you will also receive a link to watch the recorded webinar. Each session is 45 minutes including 15 minutes for Q&A.

Hot melt extrusion, process monitoring and final product verification

Hot melt extrusion (HME) is a powerful and versatile technique for modern pharmaceutical formulation development. HME can be used for many applications, from increasing bioavailability to devising novel drug delivery methods.

September 14, 2022
10:00 a.m. – 10:45 a.m. EDT
15:00 p.m. – 15:45 p.m. BST
16:00 p.m. – 16:45 p.m. CEST

Registration link ›

Downstream Processing of Itraconazole:

HPMCAS Amorphous Solid Dispersion: from Hot-Melt Extrudate to Tablet Using a Quality by Design Approach

Hot melt extrusion (HME)-based amorphous solid dispersion (ASD) offers many advantages in pharmaceutical development, but further processing of those ASD extrudates can be challenging. The presented work shows how a robust platform for downstream processing was established using a Quality by Design (QbD) approach. Different cutting techniques at the end of the extruder barrel and different milling conditions were tested for their influence on critical quality attributes (CQAs). To assist a successful scale-up, correlations from early-formulation hand-cut processing at the lab scale to industrial-applicable processes will be established.

With special guest presenter:
Saurabh Mishra, Formulation Scientist, Manager of Pharmaceutical Laboratory
SE Tylose USA Inc.

September 14, 2022
11:00 a.m. – 11:45 a.m. EDT
16:00 p.m. – 16:45 p.m. BST
17:00 p.m. – 17:45 p.m. CEST

Registration link ›

Granulation and PAT for monitoring granulation

Continuous granulation offers opportunities to overcome several challenges of traditional batch production of tablets and capsules. It is efficient and inherently scalable, and the technique has advanced to a point of true reliability and flexibility. It can also be implemented all at once, or a little at a time.

September 14, 2022
12:00 p.m. – 12:45 p.m. EDT
17:00 p.m. – 17:45 p.m. BST
18:00 p.m. – 18:45 p.m. CEST

Registration link ›

Implants and applications of vibrational spectroscopy

Implantable drug delivery systems offer several advantages over conventional oral dosage formulations. Implants allow site-specific drug administration that delivers the drug where it is needed most. Raman microscopy can help to verify the effectiveness of the process.

September 15, 2022
10:00 a.m. – 10:45 a.m. EST
15:00 p.m. – 15:45 p.m. BST
16:00 p.m. – 16:45 p.m. CEST

Registration link ›

Identification of color in pharmaceutical products according to pharmacopeia procedures

The color of a pharmaceutical product has implications towards a variety of different aspects in the drug product development process. Both USP and EP describe analysis methods needed to quantitatively determine the color of a drug product, and these methods include acquiring CIE Lab color values. To perform this analysis, the UV-Visible absorption spectra of either liquids or powders are collected and used to determine the color values of the products.

September 15, 2022
11:00 a.m. – 11:45 a.m. EDT
16:00 p.m. – 16:45 p.m. BST
17:00 p.m. – 17:45 p.m. CEST